Publications Cardiology UMCG Q1-Q2 2025

Here you can find a selection of recent publications from the Department of Cardiology at the UMCG, published in journals in Q1-Q2 2025.

• Heart failure in patients with a systemic right ventricle: A multicentre study with long-term follow-up. Ansari Ramandi MM, Budts W, Roos-Hesselink JW, Helbing WA, Egorova AD, Bouma BJ, Duijnhouwer A, van Kimmenade R, Sieswerda GT, Konings TC, Wagenaar LJ, Ubachs JFA, Berger RMF, Hoendermis ES, Voors AA, van Melle JP. Eur J Heart Fail. 2025 Apr 25.

• Heart Failure With Preserved Ejection Fraction Phenotype Is Associated With Early Symptom Onset in Aortic Stenosis and Residual Symptoms After Transcatheter Aortic Valve Implantation. Venema CS, van Bergeijk KH, Krikken JA, van der Werf HW, van den Heuvel AFM, Douglas YL, Mordi IR, Girerd N, Lang CC, Lam CSP, Leon MB, Lipsic E, Rienstra M, Voors AA, Wykrzykowska JJ. J Am Heart Assoc. 2025 Apr 16:e038786

• Signs of congestion, quality of life and short-term rehospitalization in patients with heart failure. Voordes GHD, Voors AA, Qin H, Ter Maaten JM, Damman K. ESC Heart Fail. 2025 Apr 16

• Activation of Neutrophil Extracellular Trap Formation in Patients with Heart Failure and a Preserved Ejection Fraction. Van Essen BJ, Tromp J, Gevaert AB, De Jong TV, Ouwerkerk W, Koekemoer A, Djordjevic D, Baumhove L, Tharshana GN, Conde-Knape K, Nath M, Lang CC, Samani NJ, Michaelsen NBM, Voors AA .J Card Fail. 2025 Mar 11:S1071-9164(25)00110-1.

• Response to “Regarding clinical profiles of chronic kidney disease in heart failure with reduced and preserved ejection fraction”. Voordes GHD, Voors AA, Damman K. Int J Cardiol. 2025 May 1;426:133096.

• Up-titration of medication in patients with new-onset heart failure with and without atrial fibrillation. Zandijk AJL, Santema BT, Inkelaar FDJ, van der Wal MHL, Warink-Riemersma J, Rienstra M, Voors AA. ESC Heart Fail. 2025 Feb 19.

• Beyond the gut: Systemic levels of short-chain fatty acids are altered in patients with heart failure. Palm CL, de Wit S, Gorter TM, Rienstra M, Vos MJ, Kema IP, van der Ley CP, Bakker SJL, Bakker BM, de Boer RA, van Veldhuisen DJ, Meijers WC, Westenbrink BD. Int J Cardiol. 2025 Jun 1;428:133124

• Multimorbidity Is Associated With Symptom Severity and Disease Progression in Patients with Paroxysmal Atrial Fibrillation-Data From the RACE V Study. van Deutekom C, van de Lande ME, Rama R, Nguyen BO, Tieleman RG, Weberndörfer V, Hemels MEW, de Melis M, Schotten U, Linz D, Crijns HJGM, van Gelder IC, Rienstra M; RACE V Investigators. J Am Heart Assoc. 2025 Mar 4;14(5):e034514.

• Epicardial adipose tissue and malignant ventricular arrhythmias in phospholamban p.(Arg14del) variant carriers. Mahmoud B, Cox MGPJ, de Brouwer R, van der Heide MYC, Gorter TM, Meems LMG, Wilde AAM, van Veldhuisen DJ, de Boer RA, Westenbrink BD. Eur Heart J. 2025 Mar 11:ehaf118. doi: 10.1093/eurheartj/ehaf118.

• Myocardial ketone body oxidation contributes to empagliflozin-induced improvements in cardiac contractility in murine heart failure. Voorrips SN, Palm CL, Saucedo-Orozco H, Mahmoud B, Schouten EM, Feringa AM, Sanchez-Aguilera PI, Nijholt KT, Yurista SR, van der Meer P, Silljé HHW, Westenbrink BD. Eur J Heart Fail. 2025 Mar 11.

• Identification of disease-specific pathways and modifiers in phospholamban R14del cardiomyopathy: rationale, design and baseline characteristics of DECIPHER-PLN cohort. Deiman FE, de Brouwer R, Baumhove L, Bomer N, Grote Beverborg N, van der Meer P. Neth Heart J. 2025 Apr;33(4):112-119.

• Feasibility of the absolute quantification and left ventricular segmentation of cardiac sympathetic innervation in wild-type transthyretin amyloidosis cardiomyopathy with [123I]-MIBG SPECT/CT: The I-NERVE study. Tubben A, Prakken NHJ, Ivashchenko OV, Tingen HSA, Glaudemans AWJM, Noordzij W, Nienhuis HLA, van der Meer P, Slart RHJA. J Nucl Cardiol. 2025 Mar;45:102146.

• Sex-specific risk factors for new-onset heart failure: the PREVEND study at 25 years. van Essen BJ, Emmens JE, Tromp J, Ouwerkerk W, Smit MD, Geluk CA, Baumhove L, Suthahar N, Gansevoort RT, Bakker SJL, Damman K, van der Meer P, de Boer RA, van Veldhuisen DJ, Voors AA. Eur Heart J. 2025 Apr 22;46(16):1528-1536.

• Reply to: Left atrial strain: A newly emerging prognostic marker for ST-elevation myocardial infarction. Ricken KWLM, Lipsic E. Int J Cardiol. 2025 May 1;426:133071.

• Left atrial strain predicts long-term heart failure outcomes after ST-elevation myocardial infarction. Ricken KWLM, Lenselink C, Venema CS, van der Horst ICC, van der Harst P, Pundziute-Do Prado G, Voors AA, Lipsic E. Int J Cardiol. 2025 Mar 1;422:132931.
• Nicotinamide-N-methyltransferase inhibition improves cardiac function and structure in a heart failure with preserved ejection fraction mouse model. Li S, Rodrigues PG, Chakraborty AD, Correia C, Schouten EM, Strömstedt M, Löfgren L, Persson M, Fredlund L, Rohman M, Bergström F, Akerud T, Ericson C, Kreisel K, Guzman MM, Silljé HHW, de Boer RA, Meems LMG. Pharmacol Res. 2025 Jul;217:107820.
• Individual Natriuretic and Diuretic Response in Acute Heart Failure: Insights from the PUSH-AHF Pharmacological Substudy. Beldhuis IE, Maaten JMT, van der Meer P, Coster JE, Baumhove L, Krikken JA, Nieuwland W, van Veldhuisen DJ, Voors AA, Damman K. J Card Fail. 2025 May 23:S1071-9164(25)00238-6.
• Response to ‘Simple jugular venous assessment: a new approach to heart failure’. Voordes GHD, Voors AA, Ter Maaten JM, Damman K. ESC Heart Fail. 2025 Jun 24.
• From Fuel to Code: How Ketones Drive Coronary Revascularization. Van den Hurk JJ, Schiattarella GG, Westenbrink BD. JACC Basic Transl Sci. 2025 May;10(5):608-611