Niels Grote Beverborg

Physician-scientist

Niels Grote Beverborg received his Bachelor of Science in Medicine cum laude and with honours of the Junior Scientific Masterclass in 2013. Subsequently, he combined his Masters in Medicine with a PhD in cardiology under the supervision of dr. Peter van der Meer. Niels defended his thesis entitled “Anemia, erythropoietin and iron in heart failure” on the 7th of January, 2019 and is currently seconded as a post-doctoral researcher in the lab of Prof. Kenneth Chien at the Karolinska Institutet in Stockholm, Sweden. His current research focuses on new treatments for hereditary and acquired cardiomyopathy.

Contact details

Current activities

Niels’ continued studying iron deficiency using “-omics” data in large patient datasets combined with mechanistic studies in in vitro models. Additionally, together with the Karolinska Institutet and large pharmaceutical companies, Niels is developing antisense oligonucleotides as a treatment modality for genetic cardiomyopathy, specifically caused by the PLN-R14del mutation.

My projects

PLN cardiomyopathy

Investigating and treating phospholamban cardiomyopathy

Selenium and Heart Failure

Translational research focusing on synergy between lifestyle interventions and treating HF.

My publications

High selenium levels associate with reduced risk of mortality and new-onset heart failure: data from PREVEND

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High serum erythropoietin levels are related to heart failure development in subjects from the general population with albuminuria: data from PREVEND.

Grote Beverborg N, van der Wal HH, Klip IT, Voors AA, de Boer RA, van Gilst WH, van Veldhuisen DJ, Gansevoort RT, Hillege HL, van der Harst P, Bakker SJ, van der Meer P. Eur J Heart Fail. 2016

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Definition of Iron Deficiency Based on the Gold Standard of Bone Marrow Iron Staining in Heart Failure Patients.

Grote Beverborg N, Klip IT, Meijers WC, Voors AA, Vegter EL, van der Wal HH, Swinkels DW, van Pelt J, Mulder AB, Bulstra SK, Vellenga E, Mariani MA, de Boer RA, van Veldhuisen DJ, van der Meer P. Circ Heart Fail. 2018

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Differences in Clinical Profile and Outcomes of Low Iron Storage vs Defective Iron Utilization in Patients With Heart Failure: Results From the DEFINE-HF and BIOSTAT-CHF Studies.

Grote Beverborg N, van der Wal HH, Klip IT, Anker SD, Cleland J, Dickstein K, van Veldhuisen DJ, Voors AA, van der Meer P. JAMA Cardiol. 2019

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