Hilde Groot

MD/PhD Student

With a medical background, Hilde studies the role of inflammatory biomarkers in the pathophysiology of ischemic heart diseases (coronary artery disease, myocardial infarction, ischemic heart failure). She combines genetic, experimental and clinical data in order to gain more insights into the role of inflammation. Furthermore, she is studying the role of the human gut microbiome in myocardial infarction.

Contact details

The single-cell sequencing pilot studies genetic profiles of circulating inflammatory cells at a single cell level in myocardial infarction patients. This will be done during the acute and  chronic phase of a myocardial infarction and will be compared with data from healthy controls. In addition, stool samples are also collected.

My publications

High-sensitivity C-reactive protein and long term reperfusion success of primary percutaneous intervention in ST-elevation myocardial infarction.

• Groot HE, Karper JC, Lipsic E, van Veldhuisen DJ, van der Horst ICC, van der Harst P, et al. Clin Res Cardiol. 2019

view on publisher site

Plasma interleukin 6 levels are associated with cardiac function after ST-elevation myocardial infarction.

• Groot HE, Al Ali L, van der Horst ICC, Schurer RAJ, van der Werf HW, Lipsic E, et al. Clin Res Cardiol. 2019

view on publisher site

Leukocyte profiles across the cardiovascular disease continuum: A population-based cohort study.

Groot HE, van Blokland I V, Lipsic E, Karper JC, van der Harst P. J Mol Cell Cardiol. 2019

view on publisher site