George Markousis-Mavrogenis

MD/PhD Student

George was born and raised in Athens, Greece and came to Groningen to study medicine. In 2017 he received his Bachelor diploma with honours in science. After successful completion of his master thesis at the department of cardiology, he successfully applied for the MD-PhD program, which allows students to obtain a master of medicine and a PhD in 3+2 years.  George works on elucidating the complex interplay between the immune system and the heart in heart failure and is under the supervision of Prof. Dr. P. van der Meer, Prof. Dr. Adriaan A. Voors and Dr. J. Tromp.

Current activities

George is currently investigating the involvement of numerous immune system processes and immune cell subtypes in the pathophysiology of heart failure using plasma biomarkers and full-blood transcriptomics, with the ultimate aim of uncovering promising novel therapeutic targets for heart failure patients.

George has submitted his thesis to the reading committee and it is expected that he will defend his thesis by the end of 2023.

My projects

BIOSTAT-CHF

Facilitate personalized therapies in patients with heart failure

My publications

Clinical and prognostic associations of autoantibodies recognizing adrenergic/muscarinic receptors in patients with heart failure

view on PubMed

Multimarker profiling identifies protective and harmful immune processes in heart failure: findings from BIOSTAT-CHF

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The clinical significance of interleukin-6 in heart failure: results from the BIOSTAT-CHF study.

Markousis-Mavrogenis G, Tromp J, Ouwerkerk W, Devalaraja M, Anker SD, Cleland JG, Dickstein K, Filippatos GS, van der Harst P, Lang CC, Metra M, Ng LL, Ponikowski P, Samani NJ, Zannad F, Zwinderman AH, Hillege HL, van Veldhuisen DJ, Kakkar R, Voors AA, van der Meer P. Eur J Heart Fail. 2019

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